If you look in your root Application.cfm (or Application.cfc) file, you will find code like the following:
This calls the /_config/invoke.cfm file. The framework invocation is put in the config folder to keep all configuration centralized in that folder.
From here you can change the URL variable used to reload components or scopes into which configuration settings are copied.
You can also add a "ConfigFolder" argument to the framework call to change the folder in which you store your configuration data (default is "/_config/").